Biochemical Aspect of Uric Acid Crystal Development

From FK Wiki
Jump to: navigation, search

Block B2 - Neuromusculoskeletal Problems


Biochemistry
Office:6th floor, Radiopoetro
Work-plan:None.
Pre-test:3-6 questions, short-answer.
Post-test:Sometimes. Oral only.
Lab Report:
  • Introduction
  • Reagents/Equipment
  • Procedure
  • Result
  • Discussion
  • Conclusion
  • References


Microscopic slide from this session
Microscopic slide from this session
Gout

Pretests[edit]

Batch 2011[edit]

  1. On a purine free diet, uric acid output will be: 0.1-0.5 g per day.
  2. On a high purine diet, uric acid output will be: 2 g per day.
  3. In humans, what are two pathways to form uric acid: Adenosine and guanosine.
  4. In humans, the end products of purine catabolism are: uric acid, urea, and ammonia.
  5. Gout is a metabolic disorder of purine catabolism.
  6. Hyperuricemia is caused by decreased renal excretion, increased production, and increased intake.
  7. Name three shapes of crystals: Rhombic plates, rosettes, barrel.

Final Exam[edit]

Batch 2011[edit]

  1. Dysfunction in which enzyme causes gout?
  2. What is the chemical name of uric acid?
  3. Name three sources of hyperuricemia.
  4. Uric acid output in normal condition, on high purine diet, and purine-free diet.
  5. What enzyme oxidizes uric acid to allantoin? Urease.
  6. Gout is a metabolic disorder of purine catabolism.
  7. What are the common locations for gout to manifest?
  8. What does ingesting alcohol produce that inhibits secretion of uric acid? lactic acid.

Links[edit]